Full Name The Brain
Segment Pinky and the Brain
First Episode The Monkey Song/Win Big
Voice Actor Maurice LaMarche
Catchphrases "Are you pondering what I'm pondering?"
"Stop it, Pinky, or I shall have to hurt you."
"The same thing we do every night Pinky, try to take over the world."

The Brain is an intelligent megalomaniac mouse that harbors a long-lasting desire to take over the world. He is often annoyed by his cage-mate Pinky's silliness, but it doesn't stop him from hatching up complicated schemes each night in order to achieve global domination. How ever he notes that since he was really smart that he could make the world a better place.

In You'll Never Eat Food Pellets In This Town Again, Brain has a wife named Sheila who apparently plays Billie. However, this episode was non-canonical and was meant to poke fun at WB's petty executives. Brain is heavily based on Orson Welles in both looks and vocal performance. In one episode he even tried to copy Orson's infamous radio telling of War of the Worlds.

Character info

Though he is extremely intelligent, he often misses a fatal flaw or makes a small mistake that causes the plan to completely fail. Though he never admits fault and blames Pinky for his failed attempts at world domination, he genuinely cares for him. There are a few occasions that have been completely out of his control reasons why his plans don't work.
Screen shot 2013-02-08 at 12.36.23 AM

Young Brain after just being put into a cage.

The Brain was originally a wild mouse, but was captured at a very young age and brought to ACME, where he was placed in a cage with Pinky. The two of them grew up together, and Brain's trauma caused him to strive for world domination.

The closest he ever came to world domination was in the Christmas special. He had managed to use Santa to deliver mind control dolls to every home in the world; however, as he was about to give the signal through the dolls the spirit of Christmas overtook him (after reading Pinky's letter to Santa Claus) and he instead ordered the world to have a merry Christmas.
Pinky in tears

Brain realizes that Pinky is a loyal and true friend after reading the letter to Santa

In Wakko's Wish, he fulfills his desire to rule the world (or at least be in charge of a small part of it) by becoming the prime minister of ACME Falls. He states in the end that he plans to take over the world in the sequel. There was unfortunately no sequel to the film.


Brain is bitter, rude, short-tempered, clever, self-centered, scheming, angry, irritable, grumpy, sarcastic and deadpan, but he has a soft and tender heart. He is often aggravated by Pinky's dim-witted comments and claims he's going to hurt him if he doesn't stop - a threat he quite often follows through on. On rare occasions throughout the show, it becomes increasingly obvious he does care for Pinky. The sentiment, however, is usually overshadowed by Brain's ambition for his most recent scheme.

Brain was, for the most part, based on the famous actor Orson Welles. Actor Maurice LaMarche did add, on a couple of occasions, that Brain is 65% Orson Welles and 35% Vincent Price.

The Brain has also been shown to shed tears a few times, such as after reading Pinky's letter to Santa in "A Pinky and the Brain Christmas", a letter which Pinky didn't get the chance to deliver. The letter stated that all he really wants is for his best friend, The Brain, to be happy. This makes Brain realize how much of a true and loyal friend Pinky is, and that perhaps there's more important things in life than world domination - at least on Christmas.



  • He hates being chided. Dislikes the unexpected. Cameos, the sea, leeches, clowns, Snowball; they're all the worst.     
  • Sadly and ironically, he doesn't see just how much he bullies Pinky. In "Cute Little Alienhead" (Pinky, Elmyra and the Brain), Brain gets a taste of his own medicine when the alien he has contacted starts calling him dummy boy, which angers Brain to no end. Not only that; Pinky gets in a return volley by insisting, "Aliens aren't the only ones who want to know they're valued, you know!"    
  • He has a beautiful singing voice, which he denies in "Brain's Way".


"Quiet, Pinky! You're angering me! Now, please--" [Brain's temper triggers the potion he's ingested, causing him to transform into a terrifying, muscular green-furred beast]

"How are you going to get the Earth to lose weight?"

"Your associative powers belie your small cranium, my friend."

"Do you realize what we will do with this pollen, Pinky?"

"Diets don't work."

"Pinky, are you all right?"

"Hmm, I transformed when you angered me, and transformed back when you apologized. That's it! Anger me, Pinky!"


"Come on Pinky, be a man! Like Elanor Roosevelt!"

"Snake eyes!"

"That's a simple task, Pinky."

"Elmyra, No!"

"I am not a vacuum cleaner!"

"It must be inordinately taxing to be such a boob."

"Pinky, once I take over the world, remind me to publicly snub you."

"I am not a mini-bar!"

"He'd say 'yes' if he were conscious."

"Listen, mister. If you don't like things around here, hard cheese! My cage, rules!"

"I'm not a rat, I am a mouse!"

"This Caped Oppossum is a self-obsessed nocturnal loon with a dreadful fashion sense."

"Wee Willy Pinky, are you pondering what I'm pondering?"

"Uh, perhaps you could direct us to the nearest spaceport, little girl."

"Pinky, are you pondering what I'm pondering?"

"Pinky, you are a threat to tolerance."

"Don't hurt yourself, Pinky."

"Promise me something, Pinky. Never breed."

"This is it, Pinky-O, our moment of truth. Are you pondering what I'm pondering?"

"I shall become a costumed crime fighter and thwart Johnny Badnote, overshadowing the Caped Oppossum. Then I will use the superhero's fame and forum to rule the world!"

"Pinky, if you don't stop this foolishness, I shall have to hurt you."

"My eyes...they're leaking."

"Get down from there, Pinky!"

"I'd say puberty was inordinately kind to you."

"Stop it, Pinky! Stop it! Your influence is corrupting my prototype!"


"I am not devoid of humor."

[bellows angrily] "PIIINKYYYYYYYYY!"

"I am not amused."

"Yes, that's it. We'll open a boutique and sell ladies' clothing and pollen."

"We're going to a place where the sun never sets, the size of your wallet matters, and actors and actresses slave all day."

"Some kind of jet propulsion?"

"It proved that radio was a powerful tool. And now, Pinky, the advance of technology has brought us an even more powerful tool. Do you know what that is?"

[Pinky and Brain change into their new costumes] "Call me by my new name: The Cranial Crusader!"

"Conteplating your afterlife, Pinky."

"Because we need to get to the Megastar."

"I've told you, I am not a refrigerator. I am a laboratory robot engaged in an active in an intricate scheme of galactic domination."

"I've watched a lot of Dukes of Hazard."

"Pinky, are you thinking what I'm thinking?"

"How ironic."

[baffled] "Uh...who says we can't? Now, where's the button for this thing..."

[a large telephone book has just landed on Brain, leaving him dazed] "Did you know this phonebook has three separate listings for nitro-burning funny cars?"

"My confidence in this mission is dwindling..."

"This is the last time I let comic books get in the way of intellect."

[to Snowball] "I hate you."

"We'll reach Mars before I yell 'Poit!' Pinky."


"because we're trying to take over the galaxy."

"Exactly Pinky, as they say in rustic circles, bottoms up!" [guzzles down Dr. Jekyll's formula]

"I met her today in the maze. Her name is Billie. She's of simple folk, fair and true."

"YES!" [an anvalanche starts]

"Do not mock a love-smitten mouse."

"I wish you were as smart as a tree stump, Pinky."


"I hate being chided. But she'll be gone soon, then I can begin my plans for tomorrow night. Another plot to take over the world! But first, a bath!"

"Because with me in charge, it will be a better place."

"You are going to be a help this time. Say it!"

"You just said 'Fetch me a big clown hat!'"

[being attacked by an octopus] "PINKY!!"


[speaking in sealion language] "You must get the army back at once."

"There's no time for me to give you another fish!"

"Unfortunately, it came out more like, 'I'm a big billy goat so you'd better beat it, sister.'"

"What do you want to be Pinky?"

"You can't save me!"

"Give me that stupid letter!"

"Because I'm really smart!"

"It already has, Pinklet. The question is, when does Algore start to animate?"

"Has it ever occurred to you, Pinklet, that your scarf is constricting the bloodflow to your head?

"Luckily, I know the location of a veritable Fort Knox of honey, right here in Acme Woods!"

"I hate the sea."

"Oh, look, it's time for a visit with Mr. Loyal Subject." (puts on puppet and has it say:) 'Hello, Your Highness. Hail you!' "Hello, Mr. Loyal Subject. What's the secret word for today? "The secret word for today is Brain!' "Golly, that's me!" 'That's right; it's important that our viewers must learn to bow before the Brain!' (lights flash) "Hey, you said the secret word! You win!"

"My goodness, someone's at the door. Who could it be?"

"Hello, Pinky the Unstinky."

"You said the secret word!"

"You said the secret word again!"

"OK, that's enough."

"Stop saying the secret word!"

"Errrrgh! Stop saying 'Brain'!" (lights flash)

"Stop it, stop it, stop it!"

"Okay, that's it! The secret word is not 'Brain'!"

"The new new secret word is 'pain'."

"No, but we can play Geniuses and Numbskulls."

"Like this!" [hits Pinky with his stick]

"As you know, people in today's body conscious society are obsessed with losing weight. My plan is to secretly replace all the artificial sweeteners in the world with real ones, thus rendering the world's population fat, slow moving, and completly toothless."

[speaks German] "That's German for, 'I am going to have to hurt you!'"

[Mindy put a dress on Brain] "I am mortified..."

[while babysitting Mindy] "I must rethink my present career."

[seizes Pinky by the snout] "That's it! No more Pat the Bunny, no more moonwalk parties, no more games of 'what's that smell?', and no more--"

"Come Mindy, it's time for us to conquer the world."

"By right of superior intelligence I am best suited to guide the destiny of this planet."

"My empirical powers give me the mandate."

[shouting] "Because it's something I want to do!"

"Exactly, Pinklet."

[in green-furred beast form] "No, Pinky! The pallet!"

"Because I am, now stop saying 'why'!"

"After Snowball, Pinky! He's about to engage the machine!"

"Stop being foolish, Pinky."

"I feel the need. I feel the need for expeditious velocity."

"The game does not conclude until the woman with the eating disorder ululates."

"What is Troz?"

"The irony of it all, Pinky. Years of trying to take over the world, and all I had to do was say moo."

"The Cold War is over Pinky. Now Russia is a place of free-market capitalism."

"Erm...cheating, lying and backstabbing intrigue."

"As if you didn't know."

"I am the subject of this whole conference."

"No, Pinky, it's Billie."

"I must study the operation of the Hackensack Socko Kicky-Sack Sack Kicker Factory in detail, Pinky."

"We will introduce ourselves as the only thing guaranteed to gain the respect of any American businessman: Japanese industrialists, seeking to buy the company."

"Now, remember, I am Mr. Kawasaki, and you are Mr. Hayasaka."

"Yes. We are two tiny Japanese industrialists, seeking to buy this company. I am Mr. Kawasaki...."

"Turkey-Lurky? Isn't it Mr. Hayasaka?"

"I only see five sitting sheet slitters."

"So, you sacked the cocky khaki Kicky-Sack sock plucker?"

"It might make more sense to have the sixth sitting sheet slitter's son flick the plug, if the sack pickers and the sock pluckers are behind the rubber baby buggy bumpers."

"And what, pray tell, is this?"

"I'm Kawasaki, Pinky. You're Turkey-Lurky."

"I've seen all I need to see of the Hackensack Socko Kicky-Sack Sack Kicker Factory."

"Pinky, we must take our leave, and sneak back under cover of nightfall."

"Peggy Babcock... Peggy Babcock... Peggy Babcock. Why does that name sound familiar?"

"This is it, Pinky."

"No, Pinky. This pea contains a single helium element. Once this pea is added to the Hackensack Socko Kicky-Sack Sack Kicker Factory assembly line, every Socko Kicky-Sack Sack Kicker will fill with helium the first time it is inflated. Now, Pinky, here is the plan. Remember, every step must be performed with precision!"

"You must slit the sixth sick sheet slitter's son's sheet, secure it next to the toy boat from the Hackensack Socko Kicky-Sack Sack Kickers' picnic in Secaucus, stretch it past the sack pickers' station and the sock plucker's chute, and pick a sack, pluck a sock, and flick the plug, so I can put the pea in the plucked sock with the picked sack for ballast and bounce it off the rubber baby buggy bumper, into the Parker Packard purple pewter pressure pump. Is that understood?"

"Pinky, quiet!"

"I must be fooling myself. This will never work."

"Why, yes, Pinky! That was perfect!"

"Time heals all wounds, Pinky, except the one in your head."

[sighs] "Then, just listen to me. I will shout out each step."

"Peggy Babcock?"

"Ohhhhh. Now, Pinky, schlit the seat."

"The schlick shick sleet schlitter's schleet."

"Oh, I'll do it."

"Troy boit! Tow boot! Toy beat!"


"Plick the flug! I mean flee the flack."

"Yeee--owwwww. Ow. Ooh. Eee. Aw. Ummm."

"Blinky! Bluck the flig!"

"Pig the flick! I mean, flog the plu...."

"Ahhh-hahh! Not the rugger booby biggy boopers! Yahhhh!"

"Oh no."

"Pebby Bagbop! Yawwww!"

"Piggy Bigbop!"

"Oh, never mind about that, Pinky. We must get back to the lab, to prepare for tomorrow night."

"No, Pinky. The same thing we do every night; try to wake over the turld!"

"Because you're driving me crazy!"

"Pinky! Hurry! Get out of here; save yourself!"

"Schmëerskāhøvênathon? Pinky, do you know what this means?"

(about Snowball's plan) "...and execute me in the process."

"No! Pinky, you got chocolate on my Jack-o-lantronic transmitter!"

"Stop it, Pinky, or I'll put you right back in."

"For the last time, Pinky, there is no such word as 'Chramecirum'!" [disguised as a cow]

"Moo. We are a cow. Take us to China."

"Pinky-o, tell her to stop!"

"That's the stomach, Pinky! If we drop in there, we'll be eaten alive by gastric juices!"

[Reading Pinky's letter to Santa] "Dear Santa, Hello, haha, narf. [Glares at a tearful Pinky before continuing] This year, Santa, I ask for nothing, but I wish to tell you about [haltingly] my dear friend, The Brain. He is honest and very hardworking, and only wants what's best for the world. But he gets no reward - he's only greeted with defeat. He never gives up, but I know it must be very hard. So please, take anything you have for me and give it to my best friend in the whole world, The Brain. [Looks sadly over at Pinky, who is crying due to not having given the letter to Santa when he had the chance] Love, Pinky. PS - By any chance, do you have in that big old bag of yours, the world?"

[Still teary-eyed from Pinky's letter, composing himself] "Um, ladies and gentlemen of the world, you will do as I say. For I... I command you. I command you to... [Looks over at Pinky, who is urging him on, before tearfully blurting out] Have a Merry Christmas everyone! Have a merry, merry Christmas! Joy to the world! Yes!" [Breaks down sobbing]

"Luckily, I know the location of a veritable Fort Knox of honey, right here in Acme Woods!"


"With the help from the great Leonardo Da Vinci."

"I assure you, I am not a garbage can, I am a robot on a vital mission."

"That's Brain, not Brian."

Kids' WB promo quotes

"Rise and shine, people of Earth. I am your new sun."

"If I can't take over the world, I shall shine over it! Everyone will have to look up to me, the Brain."

"Pinky, if I had arms, and wasn't a ball of glowing hydrogen, I would hurt you."

[Crossing over with Pokémon]

"Be quiet. If we catch them all, we'll be able to rule the world! Bring it on!"

"Yaaaaaaahhhhhh!!! [is tail-whipped by Charmeleon] Aaaaah!"

[gets roasted by Charmeleon] "Gotta catch 'em all..."

"Pinky, if I can teach you that Tiny Toon Adventures and Animaniacs come on weekday mornings, Kids' WB! will pay me big money, and then..."

"No, I use that money to take over the world! Say it with me: Tiny Toons."

"Yes, that's right. Then?"

"Who are you talking to?"

"Thanks for agreeing to meet with me; I really feel you're the only one who can help. You see, after five years of unsuccessful attempts at world domination, I finally figured out where I was going wrong."

"In short, I need a new partner, one whose might is equal to my intellect. In return, I'm willing to let you have all of northern Europe."

"Who asked you?!"

"I need help from you viewers. Pinky and I are being held hostage by some horrible little girl whose name escapes me right now."

"Be quiet Pinky, or I shall have to hurt you."

"What can I do for fun, Pinky? That's it! I'll send several bills to Senate for ratification, then veto them all!"

"At the key moment, I will assume control of the world's loudspeakers and bombard the masses with the most annoying sound known to mankind."

"The 24-hour deadline has passed, yet there has been no message from Earth! It is most curious. Perhaps I was too lenient!"

"Pinky, remind me to hurt you later."

Animaniacs Game Pack

"Not so hard, Pinky!"

"The same thing we do every night, Dot: try to take over the world!"

Why does he always fail to take over the world?

All of Brain's attempts to take over the world fail. There is more than one reason for this. These reasons simply consist of three basic categories.

Category One: There may be a flaw in his flawless plan that he forgot to factor in, and it isn't discovered until it's either too late to fix or the plan has already blown up in his face. For example, in the episode Opportunity Knox he forgot that gold is extremely heavy. Too heavy for a mouse to carry.

Category Two: Pinky has a natural knack for screwing things up. When he's involved in the plan's execution, expect to bear witness to a mess in the making. An example of this would be in the episode Brain Meets Brawn where Pinky had to apologize for making a mistake.

These first two reasons were explored by Brain in the episode That Smarts, in which he addresses the issues surrounding his plans' failures and builds a machine that has the ability to either increase or decrease intellect. Before using it on Pinky, Brain tells Pinky that he has done some research and has found that Pinky himself is the reason for all of Brain's failures. After using it on Pinky, Pinky becomes very smart. However, by making Pinky really smart, it changes everything about their relationship and makes it so boring. The relationship between the two mice then becomes strained as Brain tries to find a reason as to why his discovery failed and it was also due to Pinky's belief that Brain didn't like him anymore because he became very smart. In the end Pinky reverts himself back to his simple minded ways once he drains his brain and Brain figures out that he, himself is the true reason to blame for his failures. The last few seconds of the episode show the two mice having turned themselves into dummies by the use of the machine.        

Category Three: Sometimes it's merely a matter of circumstance, and neither of the mice are at fault. Something or someone interfered with their plans.   


Community content is available under CC-BY-SA unless otherwise noted.