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Wile E. Coyote is a cartoon character from the Looney Tunes series of cartoons, whose sole purpose in life is to catch and dispatch the Road Runner consistently and constantly failing in his efforts.
He gets run over by Slappy Squirrel in Little Old Slappy from Pasadena.
He was chasing Road Runner and gets hit by a truck in Bumbie's Mom.
In "One Flew Over the Cuckoo Clock", Wile E. is seen at the hospital in a wheel chair (however, his face is not shown).
Wile E. also appears in in a The Wizard of Oz parody, dressed in his batsuit from one short, in a tornado funnel in "Buttons in Ows".
He is among the cartoon characters seen in Dot's musical number in the reboot episode, "Suffragette City", where he is seen with a smug-looking face and holds up a "Vote!" sign as Dot mentions him.